Barbituric Acids A Review of Preparation, Reactions and Biological Applications

Barbiturates, which are derived from the medically significant substance barbituric acid also known as malonylurea or 4-hydroxyuracil, employed anaesthetics, sedative-hypnotics, anticonvulsants, and depressants of central nervous system. In recent years, researchers have paid great attention to compounds derivatives acid, although first was discovered in 1864 by Adolf Von Baeyer. Due its medical biological importance wide applications polymerization catalysts, plastics textiles, aqueous oil inks, polymers. The background, reactions, methods preparing been studied over last ten years.